European Organoids Symposium 2019
September 23-24 2019
Centro Congressi Fondazione Cariplo
Milano, Italy
About the conference: gathering experts in organoid technology
Great speakers. Great science
The European Organoids Symposium 2019 is organized by the LSFM4LIFE Horizon 2020 consortium to connect the scientific community working with organoids. We have invited top speakers in order to provide first-class scientific information on this groundbreaking technology.
Keynote speakers

Sylvia F. Boj
Hubrecht Organoid Technology, Utrecht (Netherlands)
Programme
European Organoids Symposium, Milan 23rd-24th September 2019
Day 1 - September 23rd
Registration
8:30-10:00
Conference venue, foyer.
Welcome
9:45-10:00
Opening address by the organizers
LSFM4LIFE session
10:00-12:30
Speakers
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Lotta Hof, Frankfurt am Main (DE)
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Nicole Prior, Cambridge (UK)
-
Kourosh Saeb-Parsy, Cambridge (UK)
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Wolfgang Moritz, Zürich (CH)
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Brigitte Angres, Reutlingen (DE)
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Lorenza Lazzari, Milan (IT)
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Bart van Djik, Maastricht (NL)
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Lorenzo Piemonti, Milan (IT)
Lunch break and poster session
12:30-14:00
Conference venue, foyer.
Keynote lecture
14:00-15:00
Madeline Lancaster, Cambridge (UK)
Neuronal organoids
15:00-16:00
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Rami I. Aqeilan, Jerusalem
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Elena Cattaneo, Milan (IT)
Young researchers
16:00-18:00
Speakers selected from abstracts
Social night
19:00-
Food, drinks, music
Day 2 - September 24th
Keynote lecture
9:30-10:30
Sylvia F. Boj, Utrecht (NL)
Technology showcase
10:30-11:30
Talks by:
Rigenerand
Kugelmeiers
STEMCELL Technologies
BioLamina
Epithelial organoids
11:30-13:00
-
Nicole Prior, Cambridge (UK)
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Margherita Yayoi Turco, Cambridge (UK)
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Nicholas Hannan, Nottingham (UK)
Lunch break and poster session
13:00-14:30
Conference venue, foyer
Epithelial organoids
14:30-15:30
-
Massimiliano Pagani, Milan (IT)
-
Emma Rawlins, Cambridge (UK)
Cancer organoids
15:30-16:30
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Marc van de Wetering, Utrecht (NL)
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Daniel Stange, Dresden, (DE)
Conference closure
16:30-17:00
Closing remarks
Organizers
LSFM4LIFE-powered team

Lorenza Lazzari
Fondazione Policlinico di Milano, Milan, Italy

Meritxell Huch
University of Cambridge, Gurdon Institute, United Kingdom

Francesco Pampaloni
Goethe University Frankfurt, BMLS, Germany
Invited speakers
Sylvia F. Boj
Hubrecht Organoid Technology, Utrecht (Netherlands)
Patient-Derived organoids for drug development and patient stratification


"Patient-derived organoids, from diseases such cancer or cystic fibrosis, are suitable for performing large scale screens, becoming an excellent in vitro platform for drug discovery and development. Moreover, in vitro response of organoids correlates with the clinical outcome of the patients from which the organoid were derived."
Elena Cattaneo
Università degli Studi di Milano, Milano (Italy)
3D organoid cultures to study Huntington’s Disease
Nicholas Hannan
Wolfson Centre for Stem Cells, Tissue Engineering & Modelling (STEM), University of Nottingham (United Kingdom)
Modelling inflammatory bowel disease using human intestinal organoids
"Inflammatory bowel disease (IBD) is a chronic inflammatory disease that affects millions worldwide. Here we use intestinal biopsy from healthy and IBD patients to generate intestinal organoids to understand disease mechanism and identify biomarkers and therapeutic targets to treat the disease."
Nicole Prior
Gurdon Institute, University of Cambridge (United Kingdom)
Liver organoids for the study of liver biology and disease



Madeline Lancaster
MRC Laboratory of Molecular Biology, Cambridge (United Kingdom)
Recent advances in brain organoid technologies and their applications to human biology
“Next generation brain organoid methods to model human neurodevelopment, function, and evolution.”
Massimiliano Pagani
Department of Medical Biotechnology and Translational Medicine, Università degli Studi di Milano (Italy)
Organoids to unveil the interplay between tumor and immune system
Lorenzo Piemonti
Diabetes Research Institute, San Raffaele Scientific Institute, Milano (Italy)
Toward a cell-based cure for diabetes
“…Insulin is not a cure for diabetes; it is a treatment”
Emma Rawlins
Gurdon Institute, University of Cambridge (United Kingdom)
Cell-cell interactions controlling normal human lung development
"The use of organoids as a tool for studying the cell and molecular mechanisms of human lung development."
Daniel Stange
University Hospital Dresden (Germany)
Modeling gastric cancer using organoids
"How organoids of human and murine origin help to dissect gastric cancer tumorigenesis"
Margherita Y. Turco
Centre for Trophoblast Research, Department of Physiology, Development and Neuroscience, University of Cambridge (United Kingdom)
Organoid systems to model the maternal-fetal interface of human pregnancy
"Our organoid systems of the maternal endometrium and the fetal placenta allow us to study the events of early human pregnancy to help understand the causes of reproductive disorders"
Marc van de Wetering
Prinses Máxima Centrum, Utrecht (Netherlands)
"Building cancer in organoids"
LSFM4LIFE session: Human Pancreas Organoids and Diabetes
In this session, the LSFM4LIFE work-package leaders and team members illustrate the achievements of the project and the outlook for clinical trials
The EU Horizon2020 project LSFM4LIFE (grant agreement # 668350), running 2016-2019, aims at the isolation and therapeutic-scale manufacture of human pancreas organoids for the cellular therapy of type 1 diabetes (T1D).
Speakers
Brigitte Angres
Cellendes GmbH, Reutlingen, Germany
Synthetic hydrogels for the expansion of pancreatic organoids.
"A mouse is not human: deciphering the needs of pancreatic progenitor cells and making them thrive in biomimetic environments."
Lorenza Lazzari
Cell factory, Milan, Italy
Translational Unit. GMP culture of human pancreas organoids for clinical trials.
"Organoids for everyone"
Joan Mir
Insphero, Zürich, Switzerland
A 3D Technology platform for functional assessment of pancreas organoids.
“Enabling high-throughput compatible, convenient and robust assays in 3D cellular models”
Lotta Hof
Goethe University Frankfurt, Germany
High-content and high-throughput imaging for pancreas organoids characterization.
"Live light sheet fluorescence microscopy shows the complexity of organoids growth and morphogenesis."
Nicole Prior
Gurdon Institute, Cambridge, United Kingdom
Isolation, growth, and differentiation of human pancreas organoids.
Bart van Dijk
Lonza, Maastricht, The Netherlands
Industrialization of Human Pancreas Organoid Manufacturing.
"Reducing manufacturing costs by scaling up. Making a human pancreas organoid culture cost-effective and thus accessible to patients."
Kourosh Saeb-Parsy
Department of Surgery, University of Cambridge, United Kingdom
In vivo assessment of function, safety and immunogenicity of organoids in regenerative medicine.
Networking opportunities
Networking with colleagues at our receptions

Social night
September 23rd 2019
After demanding scientific sessions be sure to have fun with your colleagues in the evening.
Let's meet from 19:00h on at
Torre Branca, Via Luigi Camoens, 20121 Milano MI
Young researcher award
September 24th 2019
The best two talks by young researchers will be awarded with 500 €

Sponsors





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Acknowledgement
This LSFM4LIFE project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 668350.
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